Pouneh K. Fazeli, MD, MPH
Associate Professor, Department of Medicine
Division of Endocrinology and Metabolism
Director, Neuroendocrinology Unit
University of Pittsburgh School of Medicine
We study hormonal/neuroendocrine adaptations to undernutrition and the negative consequences of undernutrition. The most common medical complication of chronic undernutrition is loss of bone mass. Using anorexia nervosa as a model of chronic undernutrition, our lab is currently studying the effects of low-dose transdermal estrogen on bone mineral density in women with anorexia nervosa. We are also studying the role and function of bone marrow adipose tissue – a fat depot that is paradoxically preserved in states of undernutrition.
Anorexia nervosa, starvation, undernutrition, bone marrow adipose tissue