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Office Location:
S720 Biomedical Science Tower South

Mailing address:
3500 Terrace Street
Pittsburgh PS 15261


Phone: 412-383-8123

Linda Sadej


Robert A. Lafyatis, MD

Professor, Department of Medicine
Division of Rheumatology and Clinical Immunology
Thomas Medsger Professor in Arthritis Research
University of Pittsburgh School of Medicine

Research Interests

My laboratory effort is focused on understanding scleroderma (systemic sclerosis), and developing novel therapeutic approaches based on identifying biomarkers of the disease process and utilizing biomarkers in clinical trials.

Our laboratory was the first Pitt lab to incorporate the 10X Genomics single cell Chromium Controller into our research both in basic research and in clinical trials.  Our lab has since become a core facility for the university community to perform single cell assays including single cell RNAseq, single cell ATAC seq, Single Cell Immune profiling of TCR and BCR and multiomic assays.

Technique Expertise or Resources to share

Single Cell Sequencing Assays, Skin and Lung single cell datasets, 10X Genomics Controller, Single Cell Data analysis support.


Single cell, Scleroderma, systemic sclerosis


Lab Members

Nina Morse Laboratory manager
Tracy Tabib Senior Research Specialist- Single Cell
Daisy Monier Senior Research Specialist – Single cell
Melissa Bulik Grad Student- Human Genetics
Rithika Behera Grad Student- IBGP
Mengqui Huang, PhD Research Instructor
Cristina Padilla, MD Rheumatology Fellow
Anna Papasoglou, MD Rheumatology Research Fellow
Eleanor Valenzi, MD Pulmonary Clinical/Research Instructor